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Symbol
Name
ID

Map2k4
mitogen-activated protein kinase kinase 4
MGI:1346869

Phenotype annotations related to nervous system

*	Aspects of the system are reported to show a normal phenotype.
	Darker colors indicate more annotations

Human Phenotypes	Anorexia
Disease(s) Associated with MAP2K4	Anorexia
pancreatic cancer

Mouse Phenotypes		nervous system phenotype	abnormal neuron differentiation	decreased corpus callosum size	decreased anterior commissure size	abnormal cerebellar Purkinje cell layer	abnormal Purkinje cell morphology	abnormal cerebellar granule layer morphology
Availability	Mouse Genotype	nervous system phenotype	abnormal neuron differentiation	decreased corpus callosum size	decreased anterior commissure size	abnormal cerebellar Purkinje cell layer	abnormal Purkinje cell morphology	abnormal cerebellar granule layer morphology
	Map2k4^tm1Ctr/Map2k4^tm1Ctr Tg(Nes-cre)1Kln/? (conditional)
	Map2k4^tm1Ctr/Map2k4^tm1Ctr Tg(CAG-cre/Esr1*)5Amc/0 (conditional)	*

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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